Abstract

The present study assessed the effects of O-anisidine hydrochloride and theameliorating effect of Quercetin dihydrate in laboratory rats. Sixteen male and thirtytwo female rats (Rattus norvegicus) were used and divided into eight equal groups oftwo male and four female rats each. The results revealed that the treatment with Oanisidinehydrochloride for 30 days (T1, T2 and T3 groups) caused significantdecrease in the males body weights, sperm count, individual and massive spermmotility, testes weights, and epididymis weights as compared with control and (T4,T5, T6 and T7) groups at (P≤0.05).When Quercetin dihydrate was offered as anameliorating agent, it showed a significant ameliorating effect by increasing the bodyweights, sperm count, individual and massive sperm motility, testes weights, andepididymis weights . When Quercetin dihydrate was offered alone in the ration of thesixth treated group (T6), it caused clear significant ameliorating effect on all spermparameters comparing with all treated groups and the sperm count was evensignificantly higher than that of control group while the other aspects were similar tothose of control group at (P≤0.05). Beside, O-anisidine caused significant decrease inthe number of pregnant females, number of delivered litters, weight of litters and sexratio, and it prevented the pregnancy from being occurred in the group where bothmale and females are treated with it (T1). When Quercetin was mixed with Oanisidinein the ration of (T7), it significantly ameliorated the pregnancy chances,number of litters and the sex ratio as compared with the other groups but it didn’treach to significant level with control group at (P≤0.05).

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The article was added to IASJ on 2015-06-26

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