Study of Histopathological Changes in the Common Carp (Cyprinus carpio) Experimentally Infected by Bacteria Aeromonas hydrophila


The present study was conducted to investigate the histopathological changes and study the histopathological changes and clinical signs of bacterial hemorrhagic septicemia caused by Aeromonas hydrophila in common carp Cyprinus carpio. The study represented by induce the infection of the disease by intramuscular injection of the bacteria in the site of left behind the front edge of the dorsal fin 1-2 cm with dose of 108 cfu/100 gm of fish body weight . distinctive clinical signs of disease were emerged after three days of induction of infection which represented by depression of fish, difficult inspiration ,swimming near the surface ,corrosion of edges and fins, exophthalmia , Ascetic and excessive mucus around the body ,Macroscopic pathological changes shows hypertrophy and congestion of kidney and spleen and necrosis of muscles . As for the histopathological changes of kidney represented by tubular necrosis with cellular infiltration among degenerated tubule and presence of fibrinous exudates in hemopiotic tissues in spleen and presence of focal necrosis in the liver and infiltration of inflammatory cells in addition to presence of severe edema between degenerated muscular bands.