Vascular Endothelial Growth Factor as Predictive Marker for Hypertension in Iraqi Adults Patients


Background: Vascular endothelial growth factor (VEGF) is considered the most potent angiogenic growth factor for the stimulation of collateral vessel growth in peripheral and myocardial ischemia and other coronary heart disease. Aim: The aim of the present study was first to assess the levels of VEGF in adult subjects with hypertension, second to find any correlation between VEGF and other studied biochemical markers. Patients & Methods: Thirty four adults with hypertension (age mean 34.55 ± 3.79 year) from outpatients of Al-yarmook Teaching Hospitals in Baghdad were selected randomly from March to April 2015. For comparison, (30) normotensive subjects which were matching to patients in age and BMI. VEGF levels were measured. Results: Biochemical parameters include FBG, HDL, and cholesterol, TG, HbA1c and PCV. Anthropometric measurements were also recorded. VEGF significantly higher (p ˂ 0.05) in patients group when compared to healthy group, as well as, significant elevation also shown in FPS, HDL and HbA1c, while TG, cholesterol, Creatinine and PCV not affected. Conclusion: VEGF can be used as diagnostic marker for the hypertension in adult patients.


Hypertension, VEGF