Study the Role of HLA-DQB1 Alleles and Interlukine-17 in Women with Rheumatoid Arthritis in Al Najaf Governorate


Objective: The study aims to detect the effect of spinal versus general anesthesia on pulmonary function and find out the relationships between patients’ pulmonary functions post- surgery and their demographic and clinical characteristics. Methodology: A comparative study design carried out through the present study in order to achieve the early stated aims. The study started from 21 December 2015 to 30 April 2016. The study conducted in Al-Sadder medical city. Quota sample of (100) patients were included in the present study, (50) patients received general anesthesia and (50) patients received spinal anesthesia. The patients’ demographic and clinical data collected through the utilization the semi-structured questionnaire and by means of interview technique with the subject, while the pulmonary functions test collected by using spirometer instrument. Data was analyzed by using descriptive statistic (percentage and Frequencies) and inferential (person s correlation coefficient, independent sample t-test, and paired t-test).Results: shows that higher of patient are within the age interval about 39-47 years old %),equal ratio of gender are male (50%)and female, there are highly significant of body mass index is normal (70%), most of patient are non-smoker (47%), most of patient non-worker is, high ratio of operation in the lower of body, all of patient without respiratory disorder, more the patient without chronic disease, The study results indicate that there is a significant effect of the anesthesia on the patients’ pulmonary functions test and the general anesthesia is negatively affect the pulmonary functions more than the spinal anesthesia. In addition, that there is a high significant relationship between the pulmonary functions pre and post general anesthesia and high significant relation between the pulmonary functions pre and post spinal anesthesia and high significant relation between the pulmonary functions post-anesthesia and the types of anesthesia.Conclusions: The study concluded that anesthesia has effect on pulmonary function.Recommendations: The study recommended that breathing techniques should use for patients before anesthesia and smoking cessation before 4-8 weeks from surgery Studies should evaluate the clinical effects of different anesthesia regimes in patients with compromised lung function, and Reduction in FVC after surgery should influence the clinician’s decision at this time when choosing between general and spinal anesthesia depends on the particular clinical situation, possible other disorders, and the surgical demands.