Evaluation of Vitamins (B6, B12, B9) and Some Biochemical Parameters in Thalassemic Children


Due to the various and multiple vitamin roles that is used to improving drug action and decreasing the negative role cause by vitamins deficiency concentration which lead to many types of anemia, included this study measuring their level . The present study was conducted in- Ibn AlBalady hospital. It includes 50 patients suffering from thalassemia major aged (13-15) years. The patients were diagnosed by the type of hemoglobin (Hb), Mean corpuscular hemoglobin concentration (MCHC) and Red blood cell count (RBC), which showed alteration in those patients . All patients were males matched in age and sex . some biochemicals parameters were studied including vitamins B6, B12 and Folic acid (B9) . Some important enzymes were tried including GOT and GPT, The study also included the measurement of Bilirubin in sera of patients and healthy controls. The results showed lower significantly in Hb levels in sera of major thalassemia patients compared to control as in RBC and MCHC. The activity of both enzymes GOT and GPT were higher in sera of patients compared to control.A significant increase of Bilirubin was found in sera of a patients.


thalassemia, Bilirubin, B6, B12, B9, GOT, GPT