Antibiotic Susceptibility Patterns of Burkholderia cepacia Isolated from Different Clinical Specimens

Abstract

In this study fifteen isolates of Burkholderia cepacia were isolated from (878) different clinical specimens collected from patients admitted to Al-Hashemyia General Hospital in Hilla city. The isolates were identified depending on their morphological properties and biochemical reaction, and underwent to Vitek 2 Compact system to confirm diagnosis. It was found that the highest percentage of isolation was from sputum specimens (53.3%). Antibiotic susceptibility patterns were studied, and the results revealed that imipenem was the most effective antibiotic against B. cepacia with susceptibility percentage (93.3%) followed by chloramphenicol (86.7%), erythromycin, trimethoprim –Sulfamethoxazole and levofloxacin with (73.3%). They exhibited moderate sensitivity to ciprofloxacin, ceftazidine (66.7%), tetracycline (60%), while B. cepacia isolates showed high resistance to gentamycin and oxacillin with (86.7%), (93.3%) respectively. B. cepacia isolates showed double and multiple resistance, and resistogram profiles were ranging from (6.7-33.3%), and showed commonest multiple drug resistance among inpatients B. cepacia isolates