Effect of The Camel's Milk on Lipid Profile in Induced Diabetic Male Rats

Abstract

This study was designed to determine the impact of she-camel milk on blood total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C).Mature, healthy and alloxan-induced diabetic Sprague-Dawley rats were used as a model for this study. Rats were divided into seven groups (six rats each) they were, healthy control group, diabetic control group and five diabetic groups fed on raw, refrigerated, frozen, pasteurized and sterilized milk respectively. At the end of the experiment ( 28 days ) results revealed a significant decrease (p<0.05) in total cholesterol (91.97, 98.32, 99.14 and 95.98 mg/100ml.respectively) and triglycerides and LDL-C and VLDL-C for diabetic rats fed on raw, refrigerated, frozen and pasteurized milk compared with control diabetic group, but an increase was noticed in HDL-C (49.01, 47.07, 47.64 and 47.63 mg/100ml. respectively ) for same groups. Therapeutic effect of camels' milk was lost after sterilization. It was concluded that camels' milk played a positive role to improve lipid profile in diabetic rats.