Oxidative stress state during pregnancy period


The present study was designed to find the relation between oxidative stress and pregnancy. The study used one hundred twenty volunteers (ninety pregnant women and thirty non-pregnant women). Then pregnant women were divided to three subgroups according to trimester (first trimester, second trimester and third trimester). then, some oxidative stress factors (MDA, GSH, catalase and TAC) were measurement. Biochemical tests showed significant (P<0.05) increase in malonedialdehyied (MDA) and significant (P<0.05) decrease in Glutathione (GSH), Catalase (CAT) and total antioxidant capacity (TAC) in pregnant women compared with non-pregnant women group. It was concluded from this study that the pregnancy led to increased oxidative stress and decreased the antioxidant factors