Hypoglycaemic Activity of Ceratonia siliqua Leaves Extracts in Alloxan-Induced Diabetic Rats

Abstract

Assessment of the proposed antidiabetic properties of either of cold and hot hydrous extracts of Ceratonia siliqua plant, on fasting serum glucose levels and serum lipids profile levels in alloxan-induced diabetic rats were studied. Both, hot hydrous and cold aqueous extract of the herb leaves of Ceratonia siliqua elicited a significant anti diabetic activity with a dose of 250 mg/kg p.o. The corresponding histological pictures of the pancreases of rats that were formerly degenerated by "alloxan" revealed their restoration after treatment with hot and cold aqueous extracts.