The use of three to five Tablespoonful per day of garlic ,olive and sesame oil mixture can improve health of patients suffering from rheumatoid arthritis disease


Background: Rheumatoid arthritis (RA) is an autoimmune disease where the body immune systemattacks different normal joint tissues organs causing inflammation of the joint lining . Rheumatoidarthritis still one of an important diseases affecting large population. Different kinds of medicinewhere used but still the needs for extra herbal medicine that assist and improve patients movementsis needed for decreasing patients compliance. This study summarized the benefit of using Garlic,Olive and Sesame oil (GOS) mixture on patients health though its anti-inflammatory and antibacterialeffects and this effect was seen after using mostly three to five tablespoonful/day. Suchresults was confirmed by decreasing most of inflammatory markers (Erythrocyte sedimentation rate(ESR), Rheumatoid factor (RF), Neutrophile count, anti-cyclic citrullinated peptide antibody (Anti-CCP) level and bacterial growth) with improving patients health. Aim of the study: to study theefficiency of garlic oil, olive oil and sesame oil mixture in treatment of Rheumatoid arthritisdisease. Methods: A 80 serum samples (27 women and 43 men; mean age 45.5 ± 13.8 years; range, 25-74 years) of patients with sign and symptoms of Rheumatoid arthritis attending Karbala TeachingHospital for Rheumatology department were studied. The patients were divided into three groups:1- Twenty- five rheumatic patients were advised to administer five tablespoonful / day frommixture containing GOS oil . 2- Thirty-five rheumatic patients were advised to administer threetable spoonful/ day of mixture containing GOS oil.3- Twenty patients were advised to administerone tablespoonful/ day of mixture containing GOS oil. All the groups were advised to use topicalointments containing mixture of GOS oil for 30 days. Inflammatory blood marker like Erythrocytesedimentation rate (ESR) , Rheumatoid factor (RF), Neutrophile count and Anti-CCP level inaddition to bacterial growth was evaluated before and after administration of GOS oral and topicalmixture.Results: The results demonstrated that the level of ESR was decreased upon oral (three and fivetablespoonful/day) and topical use of GOS mixture. While RF level decreased if the patients usefive tablespoonful/day compared to three tablespoonful/day which show slight decrease in RFlevel. However, Neutrophiles count was also found to be reduced during administration of threetablespoonful/day while dosing of five and one tablespoonful/day shows a similar level ofreductions.Anti-cyclic citrullinated peptide antibody regarded one of specific test for diagnosis of RAdisease. Five tablespoonful/day the patients describe a slight decline in the curve comparedwith (three tablespoonful/day) that will have a sharp decrease in Anti-CCP level withsubsequent improvement in patients health . However, one tablespoonful/day , have relatively asimilar effect on Anti-CCP level to that of five tablespoonful/day). Bacterial growth profile wasfound in all patients to be reduced sharply upon using GOS mixture. This decrease mostlyassociated with the use of (three tablespoonful/day, five tablespoonful/day and onetablespoonful/day) respectively.Conclusion: Administration of oral (three to five tablespoonful/day) of GOS mixture was found toreduce sign and symptom of RA disease with subsequent improvement in patients health. Suchresults was accompanied by decreased in RA blood marker (ESR, RF, Neutrophiles count and Anti-CCP ) level. In addition, to the reduction in bacterial growth. However, a further study is requiredto investigate the effect of GOS mixture in compared to other anti-rheumatic drugs effects.