MATERNAL AND NEWBORN ABO BLOOD PHENOTYPE PAIRS AND GIVING SPONTANEOUS PRETERM BIRTH
Abstract
Preterm birth is defined as delivery of baby before 37 completed weeks of pregnancy. Preterm birth can be classified in to :Extremely preterm birth (<28 weeks) , very preterm birth (28-<32 weeks) and moderate to late preterm birth (32-<37 weeks) .This study tries to detect the association between spontaneous preterm birthand maternal-newborn ABO blood group phenotypes pairs.An analytic prospective cases control study 1:1 for a sample 524 , involve 262 preterm babies (cases) compared with 262 full term babies up to the age of 1 year (control), in this study gathering information done by direct interview with the women using a designed questionnaire form and medical records, the study was conducted during the period extended from the 13th of November 2012 to 1st of April 2013 in four governmental hospitals and four health centers in Baghdad . All women and their babies were distributed according to maternal –newborn ABO blood group phenotypes pairs ,a combination of maternal –newborn A-A,B-B,O-O,AB-AB pairs are used as the reference group .Distribution of women and their babies according to the maternal –newborn ABO phenotypes pairs showed significant association between maternal- new bornA-O pairs and spontaneous preterm delivery with p-value <0.05. Spontaneous preterm birth is associated with maternal- newborn A-O pairs .This finding requires further prospective analytic study with a large sample size to confirm this result.
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