Synthesis & Antimicrobial Evaluation of Open Chain of Organo–Selenium Compounds

Abstract

The organo-selenium compounds are one of important organic compounds in synthesisof different compounds and as anti microbial .The target organo –selenium compounds [3-7]were synthesized from the reaction between diethyl malonate and 4-amino benzoyl chloride toproduce compound [1] ,which is react with sodium hydrogen selenide to give correspondingsodium aroylselenide [2] ,which is react with one of aroyl derivatives as shown in scheme (1)to produce compounds [3-7].All the synthesized compounds have been investigated usingdifferent chemical techniques ,such as ,(C.H.N)-analysis , (H.NMR–spectra ,FT.IR–spectra ) ,melting points and biological study.