Evaluation Biological Activity of Some Chemical Compounds Contain Amide group or Imine group

Abstract

The study was carried out in the Laboratory of public health , directly of health for the period from 3/ 4/ 2016 to 20 / 12 / 2016 on some prepared compounds that contains amide or amine group in concentrations ( 50, 100, 150) mg / dl . To detect their inhibitory effect on pathological micro –organism ( Escherichia coli , pseudomonas aeruginosa , proteus spp. And staphylococcus aureus) , using the modified agar diffusion method as a culture media . Some compounds containing amide group in compounds( 2, 8, 9) showed inhibitory effect on pseudomonas aerug:nosa while compound (11) has inhibitory effect against pseudomonas ,This effect was attributed to that the compounds (2 , 8 , 9 )contains more than one pyridine ring in addition to containing many amide groups , while the compound (11) contain mercury in addition to pyridine rings and amide groups .