Cytological Findings in Patients with Haematuria

Abstract

ABSTRACT:BACKGROUND:Regardless of the accessibility of more up to date and more modern methods of investigations, urinary cytology still remains the most regularly utilized non-invasive investigation for the diagnosis of cancer of the bladder.OBJECTIVE:To assess the helpfulness of urine cytology in assessment of patients with hematuria for the presence of malignancy.PATIENTS AND METHODS:A total of 1560 recently voided urine samples got at private clinics from patients with hematuria, whether gross or microscopic, over a time of three years were incorporated in the study. Physical and microscopical (cytological) examination done for all samples.RESULTS:Among these cases of hematuria incorporated in the study, 23.7% (370 cases) were found to have positive finding of atypical cells. In these cases with atypia, 48.7% (180 cases) were proved to have malignancy both with cystoscopic findings and the histopathological biopsy. The remaining cases of atypia were found to be reactive, either due to instrumentation or foreign body. In an extensive number of cases of hematuria, that is, 1190 cases (76.3%) no atypical cells were identified.CONCLUSION:Urine cytology can distinguish urothelial cells changes and high grade bladder tumor so it is a good tool particularly with coordinated effort amongst clinician and cytopathologist. Urine cytology can be utilized as an adjunct test in assessment of patients with hematuria.