تأثير السيلينيوم والزنك في التركيب النسيجي للفائفي في خنازير غينيا الممنعة بلقاح التيفوئيد

Abstract

The purpose of this study is to determine the effect of the two minerals zinc ,and selenium the histological structure of intestine. thirty guinea pigs were divided in to fiveGroups(6 animals for each Group).the 1st group (S1) supplied with a selenium (0.02milligram) ,the 2nd group(S2) supplied with (0.04 milligram). 3rd group (Zn1) supplied with azinc (0.08 milligram), while the 4th group (Zn2) supplied with (0.16 milligram).the last groupserved as a control group received distill water instead. (Animals were treated daily withthese minerals using stomach tube for two months).Infiltration of lymphocytes and phagocytes in particular polymorphonuclear cells (PMNs)was noticed in ileum sections. Dilation of blood vessels was seen in all treated groups.Presence of some spherical unidentified bodies with out nucleus was also detected. Epithelialcells were hypertrophied.As a conclusion, it was seen that zinc and selenium affect cellular and humeral immunitypositively or negatively depending on the dose given. The ultra structure of certain organswas dearly affected.