Synthesis and biological evaluation of some Benzimidazole derivatives

Abstract

Group of benzimidazole derivatives are considered as an important class of compounds; they are present in a major of products with broad spectrum in industrial and biological activities. Several of derivatives that have been efficiently synthesized for -1H-benzo[d]imidazole as starting material to Synthesis of some new Schiff bases ,2-azetidinone and 4-thiazolidinone derivatives .The structures were characterized by FTIR and ¹H-NMR spectra. All The synthesized compounds were screened for their antimicrobial activities against two (gram +ve) and (gram -ve) kind of bacteria s well as fungi using the micro dilution procedure and compared with amoxicillin activity.