FREQUENCY OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS

Abstract

Background and objectives To determine the frequency of left ventricular systolic dysfunction in chronic obstructive airway disease patients and its relation to age, gender, duration of smoking and other factors.Methods A case series study of forty two chronic obstructive airway disease patients (mean age 63.64±10.21 years) were studied for assessment of left ventricular systolic dysfunction using 2D and M-mode echocardiography with assessment of ejection fraction for all patients.Assessment of clinical parameters and biochemical parameters. The age and gender of the patients were assessed. Duration of smoking and the number of pack per year were also calculated. The study was carried out in the respiratory care unit and general medical units of Ibn-Sina Teaching Hospital.Results Forty two chronic obstructive airway disease patients 36 males (85.7%) and 6 (14.3%) females (mean age 63.64±10.21 years), were studied for assessment of left ventricular ejection fraction. Among the 42 patients only 9 (21.4%) had left ventricular ejection fraction with 2(22.2%) among females and 7 (77.8%) among males, (p= 0.382), The Mean age of left ventricular ejection fraction group was found to have no significant correlation at (p=0.442). Age compared with the groups of left ventricular ejection fraction, this correlation was not significant ( p=0.267). The mean duration of smoking and pack years showed no significant association with left ventricular ejection fraction (p=0.618 and p=0.348 respectively). Patients characteristics show no sensible statistical correlation to LVSF (p =0.338), (p =0.42, p =0.26), (p=0.163, p=0.288, p=0.463) in sequence.Conclusions The frequency of left ventricular systolic dysfunction in chronic obstructive airway disease patients was 21.4 %. Age, duration of smoking and pack years in addition to other patient’s characteristics didn't demonstrate a significant relation to left ventricular systolic function in chronic obstructive airway disease patient. More sophisticated tools should be used for evolution of left ventricular systolic dysfunction in chronic obstructive airway disease patients.