METABOLIC SYNDROME AND COLORECTAL CANCER IN DUHOK, KURDISTAN IRAQ

Abstract

Background: Increasing evidence arguing the association between metabolic syndrome andcolorectal cancer in general population is in progress. Since there is a lack of information aboutthis issue in Duhok population, the present study was conducted to investigate the associationbetween metabolic syndrome and its components in patients with colorectal cancer.Methods: A case control study was conducted on 158 subjects, 79 patients with histologicallydiagnosed colorectal cancer and 79 apparently healthy subjects. Demographic information wascollected for all subjects through an interview. Components of metabolic syndrome includingabdominal waist circumference (WC), blood pressure (BP), fasting serum glucose (FSG),triglyceride (TG) and high density lipoprotein-cholesterol (HDL-ch) were measured.Results: Of the seventy nine patients with colorectal cancer, 23 (29.1%) had metabolicsyndrome as compared to 20 (25.3%) of the healthy subjects, with rates of 20.2% and 7.6% formales and 8.9% and 17.7% for females, respectively. Patiexhibited a significantly higher prevalence of metabolic syndrome than did the healthy subjects(odds ratio= 2.08, p= 0.024).Conclusion: Patients with colorectal cancer may be associated with increased risk of metabolicsyndrome in a Duhok population, particularly among males and older age group.