ANNUAL INCIDENCE OF CONGENITAL HYPOTHYROIDISM IN SULAIMANI CITY-KURDISTAN REGION/IRAQ

Abstract

Background: Congenital hypothyroidism is one of the most common preventable causes of intellectual disability. Most neonates born with congenital hypothyroidism are normal on clinical examination. Hypothyroidism in the newborn period is almost always overlooked, and as a result delay in management will cause profound neurological insult and mental retardation. Neonatal screening in Sulaimani city (center of Sulaimani governorate in north of Iraq) had started in 2013 for screening of Phenylketonuria, congenital hypothyroidism and glucose 6 phosphatase deficiency.Subject and Method: All neonates born in Sulaimani city including all hospital deliveries (both private and public governmental hospitals) in addition to the home deliveries that were referred to (Registration Bureau of Births and Deaths) during the period from January 1st to December 31st 2014 were included. Thyroid stimulating hormone was measured from heel prick blood samples obtained from neonates aged between 3 and 10 days. Neonates showing a TSH level of ≥ 5mIU/L were recalled to Sulaimani pediatric teaching hospital for confirmation of diagnosis. Aim of our study was to determine annual incidence of congenital hypothyroidism in the city.Results: Among 13050 neonates screened for congenital hypothyroidism, 75 (0.5%) were recalled (TSH, ≥ 5mIU/L). Congenital hypothyroidism was detected in 11 (14.6%) recalled neonates (incidence of congenital hypothyroidism in our study 1 in 1186 live births).Conclusions: According to this result, we concluded that Sulaimani city have high incidence of congenital hypothyroidism and in future, all newborn should be screened in this region including district areas.