Effect of Aqueous Extract of Rosmarinus officinalis on Kidney and Liver of Male Rats Experimentally Infected With Diabetic


AbstractThe present study was designed to investigate the effect of aqueous extract of rosemary onsome organs such as kidney and liver of diabetic rats . Twenty eight adult male albino rats wereequally divided into four groups ; the first group gulped with distilled water which consider as thecontrol group .The second group administered the aqueous extract of rosemary , The third groupexperimentally diabetic by alloxan that induced many histological changes in the kidney and liverwhile the fourth group diabetic and treated with aqueous extract of rosemary .Histological changes were observed in kidney which included contraction of glomeruli ,enlargement of space Bowman's capsule , degeneration and necrosis of renal tubules , haemorrhage ,absence of glomeruli , aggregation inflammatory cells , degenerative and necrosis of glomeruli , thenthe histological changes was advanced to arrival to death of glomerulus , perfect closed to canal ofrenal tubules , hyperplasia and venous congestion . Diabetic caused in liver some histologicalchanges as aggregation inflammatory cells , edema in central vein , necrosis , degeneration ofhepatocytes, haemorrhage , enlargement of sinusoids , congestion of the central portal vein ,vacuolation of hepatocytes and fibrosis .Histopathological examination of the rat's organs confirmed this amelioration of healthshowing that using of aqueous extract of rosemary can reduce pathological changes in kidney andliver . This study clearly demonstrated that administration of aqueous extract of rosemary alleviatesthe harmful effects of diabetic induced kidney and liver damages .