Synthesis of Some Substituted Pyrano 1, 3-oxazine

Abstract

Abstract7-Chloro-2- methyl thio-2-N-ethyl carbazato, 2N-acetyl tyrosyl hydrazido 4,5-dioxo pyrano [ 3, 4-e ] - 1, 3-oxazine -4, 5-dione [2] , 2, 7-di(N-ethyl carbazato) 4,5-dioxo pyrano [ 3, 4-e ] - 1, 3-Oxazine -4, 5-dione [3] and, 7- chloro 2N-acetyl amino acid hydrazido , 2N-benzoyl amino acid Hydrazido-4,5-dioxo pyrano [3, 4-e]-1,3-oxazine 4, 5-dione [4] were synthesized by standard methods. The pyrano -1, 3-oxazine [1] was prepared from condensation of two moles of malonyl chloride with methyl or benzyl thiocyanate. Spectroscopic characteristics (IR, NMR) of the pyrano -1, 3-oxazine derivatives are presented and discussed.