Status of Certain Elements in Patients with Polycythemia

Abstract

Background: Polycythemia" (erythrocytosis), is a condition characterized by abnormal increase in circulating red blood cells (RBCs) number resulting in an increased "PCV" (packed cell volume). Objective: Measure the levels of some trace elements in serum of patients with polycythemia. Patients and Methods: the study included 70 polycythemia patients (61 males and 9 females), their ages ranged 18-60 years, and 20 apparently healthy, their age and gender matched with the patients as a control group. The levels of (Fe, Zn, Pb and Cd) were measured in both patients and control. Results: Results obtained from this study showed that the male was affected more than female, male: female ratio (6:1) and the majority of patients were aged <20-29 years. A highly significant increase (p<0.01) in the level of serum iron, Pb, and Cd in polycythemia patients in comparison with healthy control. Results of zinc level in serum showed a highly significant decrease (p<0.01) in the polycythemia patients when compared with control group. Conclusion: The current study has been shown that males were affected more than females with polycythemia. Also indicate that minerals may play a significant role against a variety of diseases and processes.