Evaluation of Some Material to inhibit Biofilm Formed by Acinetobacter baumannii Isolates

Abstract

The study has included the ability of Acinetobacter baumannii (isolated from clinical infections and hospital environment) to form a biofilm and investigated the possibility of inhibition this biofilm by using some materials: EDTA, five amino acids and five plant extracts.The results showed that all isolates of A.baumannii had a good ability to form the biofilm (100%). Four isolates which had strong former of biofilm which were selected as well as a standard isolate (A. baumannii ATCC19606). The inhibitory effect on biofilm formation was investigated. EDTA had a good inhibitory effect, also, all amino acids showed good inhibitory activity , with the best inhibition in Glutamic acid at a concentration of 50 mM, while plant extracts varied in their inhibition ratio to inhibit the biofilm, turmeric, cloves and rosemary had a good inhibitory effect, Bay leaf has the ability to inhibit the biofilm formation but less than others, while the plant extract of the Myrtle did not show any inhibition activity.