Synthesis, Characterization and Study of Antibacterial and Electrical Conductivity of New Schiff Bases from Thiophene -3-Carboxyaldehyde and Two Different Para Substituted Aniline

Abstract

Schiff base derived from (3-thiophene carboxyaldehyde with p-amino aniline, and 4-N, N-diethyl aniline) has been prepared and characterized by Infrared and, and C.H.N. elemental analysis. Results of the in vitro antibacterial activity showed that the N-[(thiophene-3-yl) methylidene]-4 (N, N diethylamino) benzene (compound A) was found to be more active than N-[(thiophene-3-yl) methylidene] -4-nitrobenzene (compound B) against most pathogenic bacterial strain for both of Gram-positive bacteria, Staphylococcus aureus and Gram-negative bacteria, such as E. coli under study. Some of these compounds showed potential antimicrobial activities. In addition, the electrical conductivity of new Schiff bases was characterized; new Schiff bases were showed high electrical conductivity and that increase of ability to prepare anew-organic diodes.