Measurement of Some Antioxidants in Serum of Infected Pregnant Women with Toxoplasmosis

Abstract

The study involved measurement of medical, biological and antioxidant importance of toxoplasmosis and the effect of the causative agent, Toxoplasma gondii ,on the level of the biochemical parameters in the serum of 225 pregnant women infected with toxoplasmosis compared with225serum of women infected as control group. The criteria taken into consideration are: Glutathione (GSH) , Albumine (Alb) , Uric acid (UA) , Malondialdehyde (MDA) , Peroxinitrate (No).The Results showed: A significant increase (p≤0.01) in level of GSH, MDA and NO whereas Alb and U.A decreased, compared to control group. Interference between infection and pregnancy periods showed an significant increase (p≤0.01) in level of GSH during 1-3 months pregnancy period and MDA and non- significant increase in level of NO during 6-9 months pregnancy period. Alb and UA levels decreased, as significantly (p≤0.01) in serum of pregnant infected women.