Measurement of the Levels of Salivary Lipocalin-2 and C - reactive protein in Women with Polycystic Ovarian Syndrome

Abstract

The aim of the present study is to investigate salivary lipocalin-2 levels as well as C-reactive protein (CRP) in women with and without polycystic ovary syndrome (PCOS). Lipocalin-2 levels and C-reactive protein were measured in 104 women within the age group of (20 – 29) years were divided into two groups. Group I consisted of 55 diagnosed female patients of PCOS and Group II comprised of 49 female age matched control group with normal menstrual cycles. Highly significant differences were found using t-test in inter group comparison. Levels of lipocalin-2 in PCOS group were decreased significantly compared to the control group (p ˂ 0.05), while the salivary level of CRP were increased significantly in the PCOS group (p ˂ 0.05). Salivary levels of lipocalin-2 were found to be low whereas CRP were high among women with PCOS. It was suggested that the measurement of salivary lipocalin-2 and CRP may be specific method for making a diagnosis of women with polycystic ovary syndrome.