Effects of halothane and isoflurane on QT interval in young patients underwent hemorrhoidectomy

Abstract

ABSTRACT: Background Long QT syndrome (LQTS) is a heart rhythm disorder that can potentially cause fast, chaotic heart beats. These rapid heartbeats may trigger a sudden fainting spell or seizure. In some cases, your heart may beat erratically for so long that it can cause sudden death. The aim of study is to evaluate the effects of halothane and isoflurane on QT interval in patients underwent hemorrhoidectomy. patients and methods ECG were recorded in operative theater at al-shurgat general hospital just before surgical operations and directly after end of operation , 37 young , healthy patients were participated in this study 29 male and 8 female (n=17)received halothane (20) received isoflurane. Results: The mean and standard deviation of participants age and duration of operation was considerably higher among those who received halothane in comparison to isoflurane and differences was statistically significant and the mean of age was 29.35±5.958 years with halothane and 24.55±4.893 years with isoflurane , (p-value 0.011) and regarding the mean of duration of operation was 19.47 ±3.243 minutes with halothane and 16.75±3.240 minutes with isoflurane use ,(p-value 0.023) Conclusions the present study conclude that maintenance of anesthesia with halothane might prolong the QT-interval and did not result in arrhythmia while , with isoflurane was not associated with alterations in the QT-interval and induced no changes in cardiac rhythm.