Prophylactic role of sweet almond (Prunus amygdalus) suspension in healthy and experimentally induced diabetic rats


The current study aimed to determine some positive prophylactic effects of sweet almond suspension (SAS) on blood glucose and lipid profile of experimentally aloxan induced hyperglycemic male rats. Thirty male adult rats divided randomly into two equal groups, prevention group treated with sweet almond suspension for 60 days at two doses 1.42 or 2.84 g/kg of body weight (PD1 and PD2), and then hyperglycemia was induced by using single dose injection of alloxan (150 mg/kg of body weight). There was significant increase in means values of glucose and the concentrations of total cholesterol (TC), Triglyceride (TG), low density lipoproteins cholesterol (LDL-C), very low density lipoproteins cholesterol (VLDL-C), and low rate concentration of cholesterol in high density lipoproteins (HDL-C) after five days of injection compared with pretreatment values and after 60 days of treatment with SAS values. In conclusion there was protective effect of sweet almond suspension on hyperglycemia and hyperlipidemia in two experimentally groups, especially 2.84mg/Kg BW.