Comparison of the effect of intravenous phenylephrin and ephedrine in treatment of hypotension after spinal anesthesia in cystoscopic surgery

Abstract

Background: Hypotension may accompany cystoscopy during spinal anesthesia for which a variety of measures have been considered and none of which has accepted wide agreement. For that reason the present study was conducted. Aim of the study: The objective was to study the changes in blood pressure during cystoscopy under spinal anesthesia in two groups of patients, one on ephedrine and the other on phenylephrin.Patients and Methods: 100 patients were randomly assigned to two equal groups (n = 50). Randomization was done according to surgery list. Group 1 received ephedrine while group 2 received phenylephrine.Results: Regarding systolic blood pressure, there was no significant difference in mean systolic blood pressure at baseline reading (P> 0.05); however, it was significantly higher in group 2 than in group 2 during follow up. Regarding diastolic blood pressure, there was no significant difference in mean diastolic blood pressure at baseline reading (P> 0.05); however, it was significantly higher in group 2 than in group 1 during follow up (P< 0.05). Regarding heart rate, there was no significant difference in mean heart rate at baseline reading (P> 0.05); however, it was significantly lower in group 2 than in group 1 during follow up (P< 0.05). Conclusion: Phenylephrine is better than ephedrine in controlling hypotension after spinal anesthesia in cystoscopy.