Effect of acyclovir sodium on some biochemical markers in local male rabbits

Abstract

The current study was carried out to examine the effect of acyclovir on liver and kidney functions of local rabbits. The indicators studied included AST, ALT, ALP, Urea, Uric acid, Creatinine. The experiment was designed with two groups (6 rabbits in group), the first is control group (C) and second group is (G) that was treated with acyclovir drug. Results showed a significant increase in the level of liver enzymes activity (AST, ALT, ALP) in G group compared with control group. Also, a significant increase in the level of Uric acid in G group compared with control group, but no significant differences in the levels of Urea and Creatinine between group (G) and control group.