In Vitro Antimicrobial Activity of Aqueous-Methanolic Extract of Populus sp. Leaves

Abstract

Plants are a rich source of giving benefit natural products, includingantimicrobial agents. The current study was designed to evaluate the antimicrobialactivity of Populus sp. leaves that the aqueous methanolic extract (200 mg.ml-1) of theleaves revealed antimicrobial effects against some microbial pathogens in which thehighest inhibition zone was recorded against Candida albicans followed byStaphylococcus aureus but no effects on the growth of both Streptococcus mutans andKlebsiella sp. The chemical tests appeared that the extract contains sterols, terpenoids,carbohydrates, glycosides, flavonoids, tannins, proteins, amino acids, and saponinsglycosides while alkaloids were not detected. GC-MS analysis detected the aqueousmethanolic extract has four compounds are {2-Pyridineacetaldehyde,[2-(2-pyridinyl)ethylidene]hydrazone}, {n-Propylamine, N-acetyl-3-[2-acetyl-3,4,5-trimethoxyphenyl]-},{1-(Methyl propyl)-4-(1’,1’,2’-trichloro-3’-ethyl allyl)benzene} and {1H-Indole, 5-methyl-2-phenyl-}.