Prevalence of hyperandrogenism in Iraqi women with polycystic ovary syndrome

Abstract

Polycystic ovary syndrome (PCOS) is a mainly common endocrine disorder.Hyperandrogenism is the major standard in the diagnosisof PCOSdevelopment.Eighty women diagnosed with PCOS and twenty healthy women(aged20-40 years)were enrolled in this study which was conducted at the infertility clinicof Kamal AL-Samaraay Hospital/ Baghdad. The diagnosis of PCOS was madeaccording to the Rotterdam criteria. Body mass index (BMI, Kg/m2)was calculatedby a specific formula. History of menstrual irregularity, hirsutism, acne, andalopecia was taken. Hormone levels in serum, namely luteinizing hormone (LH),follicle stimulating hormone (FSH), and testosterone were measured in all patientsand control subjects.There was a statistically significant difference (P <0.05) in theBMI between the PCOS and control women.Also, the prevalence of overweight andobesity was much higher in PCOS women than in their matching control. The serumlevels of LH, FSH, and testosterone were significantly different (P <0.05) in PCOSas compared to healthy women. Clinical hyperandrogenism (hirsutism and alopecia)were present in most of PCOS women, while acne wasa less useful clinical sign ofhyperandrogenism.Inaddition, the prevalence of hirsutism and alopecia wasincreased in obese when compared with overweight and lean PCOS women.