The inhibitory effect for Acillia conferta and Echinops charadinii from Asteraceae family in some microbe species


The present study was designed to explore the biochemical properties and microbial activity of two natural plant species (Achillea conferta، Echinops charadinii). Biochemical analysis revealed the presence of different types of secondary metabolites such as (turbines، phenols and flavonoids). Achillea conferta showed a higher qualitative and quantitative amount of these compounds compared to E. charadinii. The methanol extracts of the two plant species were evaluatedfor antibacterial activity against five medically important pathogens: Staphylococcus aureus، Bacillus pumilus Escherichia coli، Pseudomonas aeruginosa، and one fungus Candida Albicans. The results showed different activities against all the tested pathogens in the different concentrations. Staphylococcus aureus was the most susceptible pathogen to A. conferta 100mg/ml in comparison to Tetracycline. (14.6 – 12.1 Respectively). The concentration 100 mg/ml was higher than all the other concentration in both species of plant in A.conferta scored (9.4-14.6) mm diameter of inhibition ,in E.charadinii scored ( 8.4-12.8 ) mm in all bacterial species except for the fungal species C.albicans wich did not record any inhibition, In conclusion، A. conferta methanol extract could treat diverse human bacterial pathogens due to its high antimicrobial activity.