Antibiotic Resistance of Bacteria isolated in Urinary Tract Infections in Erbil City.

Abstract

Urinary tract infections (UTIs) are the most unnoticed diseases worldwide. The resistant bacteria in UTI against commonly prescribed antimicrobials is coming forward with a daily demand for the management of antimicrobial treatment in health services. To estimate the resistance evolution of bacteria causing urinary tract infections to commonly used antimicrobials and to evaluate the options for treatment of UTIs. A total of 43 uropathogens of Gram- negative and Gram-positive bacteria were identified by using highly automated VITEK®2 System in Rizgare hospital; Erbil, Iraq; From January 2016 to December 2017. Four hundred eighty-two Urine samples from patients were cultured on appropriate bacteriological media and antibiotic sensitivity was determined by using disc diffusion method. From 482 urine specimens 80 % had positive results for bacterial cultures further more Among the 482 uropathogens, 184 samples tested for Extended-spectrum beta-lactamase (ESBL) which 94% was found to produce ESBLs. E-coli was the most common agent of UTIs (41.3 %) followed by Staphylococcus spp. (19.9%); Klebsiella spp. (11.6 %); Streptococcus spp. (7.3%); Pseudomonas aeruginosa (5%), Sphingomonas paucimobilis (4.1%); Enterococcus spp. (3.1%); Proteus mirabilis (2.9 %); other (4.8%). The disk diffusion assay proved that high degree of resistance among pathogens was to ampicillin; aztreonam; cephalothin; clindamycin; tetracycline. The lowest resistance was to amikacin; ciprofloxacin; imipenem and nitrofurantoin. Supervision for using favorable antibiotics and reducing the infection are very important.