Comparative study between usage of medicine containing a mixture of Dapoxetine and Tadalafil with the usage of these drugs separately in treatment of rapid ejaculation


A study was conducted on 58 patients aged from 18-63 years old, they suffering from rapid ejaculation and all their Intravaginal ejaculation latency time (IELT) were less than 2 minutes. This study done at Erectile dysfunction unit in Al-Muthana teaching hospital for a period of 1 month (March/2019). The patients were divided into 2 groups: Group 1: Patient received 30 mg of Dapoxetine 1hr before coitus and 10 mg of Tadalafil 30 min before coitus. Group 2: Patient received Dapoxetine 20 mg + Tadalafil 10 mg mixed in one tablet 1 hr before coitus. The result of our study revealed that the IELT before treatment was less than 2 minutes in both groups, after treatment the IELT increased significantly (P≤0.05) in group 1 and group 2 (337.9±3.72 and 222.4±2.88 seconds) respectively. The IELT in group 1 was increased significantly (P≤0.05) compared to IELT in group 2 after treatment. In conclusion, the administration of Dapoxetine before 1 hr. of coitus and Tadalafil 30 min. before coitus (G1) gave a good results in increasing of IELT as compared to mixture of these drugs in one tablet.