Alkaptonuria, a rare inherited disorder: a case report and review of literature


A 70 year old male patient from Erbil city, Iraq, complaining of gradually increasing pain and stiffness in the lower back over the last 50 years. He consulted many doctors and was misdiagnosed as having (prolapsed disc, Ankylosing spondylitis, Osteoarthritis). He was put on analgesics, anti-inflammatory drugs, hard bed .It gave him some relief but the pain and stiffness recurred again over a large area of the spine on stopping the treatment. For the past 20 years, the patient had pain in his hip joints too. There was no history of fever, trauma, oral ulcers, acute abdominal pain, dysuria or recurrent diarrhea. The urine had normal color when voided but the patient has also had brownish black staining of underwear since childhood