Comparison Between Garlic And Yomesan As Anthelmintic For Hymenolepis Nana Infection In Vivo And Vitro

Abstract

This study was carried out to compare the efficacy of yomesan and alcoholic extracts of garlic on Hymenolepis nana infection, in vivo and vitro.In vivo study, Balb C mice was used, to compare the efficacy of 50 mg/Kg B.W. of yomesan with different doses of alcoholic extracts of garlic (250 , 500 and 750 mg/Kg B.W.).It was found that the efficacy of yomesan had reached 100% after 11 days post – treatment, while the efficacy of 500 and 750 mg/Kg B.W. of garlic reached 100% after 15 days after treatment .For vitro study, special nutrient broth media was used. It was found that the addition of 1000 mg /ml of yomesan had paralysed and killed worms within 5 minutes, while garlic killed them within 30 minutes.