Study cells immune response by using a killed suspension of Pseudomonas aeruginosa as oral vaccines.


This study was conducted in order to investigate the effect of pseudomonas aeruginosavaccine on stimulating of cell mediated immune response in laboratory white mice.The result revealed the high increased weight of spleen and mesenterial lymph nodes in thevaccinated animals in contrast to the organs of the control group. The morphological changesin these organs indicate indirectly the high immunological activities of them, beside theactivation of kupffer’s cells in the liver of the vaccinated lab. animals.This study appeared a hight interaction between the cellular immune system and the orallyadministrated whole cell of Ps. aeruginosa bacteria.