Synthesis and Characterization co-Polymer of Aspargine and Cephalexin


Abstruct In this work a new peptide-base polymer were synthesized by polycondensation of cephalexinyl chloride and asparginyl chloride. This synthesized biopolymer is especially interesting because its primary structure allows the specific cleavage through amide group , can also be used for site specific release of drug as we expected. The physical properties of [C3] were measured. , FT-IR , 1H-NMR and UV. Spectroscopy used to characterized the polymer [C3]. S % was calculated in water, and controlled release was studied in different pH values at 370C.