Left Ventricular Function in Early Stages of Ischemia


ABSTRACT:BACKGROUND:Ischemic heart diseases are common diseases that influence the heart performance via the changesoccurring in cardiac muscles resulting from the disease. These changes can affect the left ventricular wall,septum thickness and an eventual effect on the cardiac performance.AIM OF THE STUDY:The merit of this work is to investigate the effects of left ventricular function on patients who suffer fromearly ischemic heart.METHODS:Twenty five patients complaining from chest pain and diagnosed as angina were subjected to ourinvestigation, they were free from other cardiac diseases and have no previous heart attack their averageage was (52.85±12.69 years old). Eighteen normal individuals (control) with average age (48.33±12.55years old) are chosen and are free from any disease. M-mode, 2- dimensional parasternal long axis viewwas used in the measurements of LV interdiameter, septum and posterior wall thicknesses. Dopplerechocardiography tracing of four chamber apical view was obtained to indicate the ejection time andmitral flow velocities at early diastole E and at atrial contraction (end of diastole) A.RESULTS:The effect of early IHD was found on the interventricular septum (decreased by 44.18%), posterior leftventricular wall (decreased by 47.62%), fractional shortening (decreased by 28.93%), and ejection fraction(decreased by 20.05%). There was no significant change observed on the A/E ratio but a significantchange was seen on E wave only.CONCLUSION:In early of IHD, ejection fraction and percentage changes of wall thickness indicate cardiac performance.In addition reduced early mitral flow velocity is more frequent than the change in early to late mitral flowvelocity ratio.