Immunization of albino mice against secondary infection with Hydatidosis by using protoscoleces treated with direct electrical current

Abstract

Immunization of BALB/c mice against secondary infection with Hydatid disease, by using protoscoleces (PSC) treated with direct electrical current for 2 min., was investigated.Injection with about 2000PSC treated with direct current 5.77mA/cm2, followed by injection with challenge dose, reduced cyst numbers (95.69%), Whereas, injection with PSC treated with direct current 11.82mA/cm2 reduced cyst numbers (93.47%) in mice 3 months post infection.Treatment with direct currents led to reduction of liver index and increase of spleen index within immunized groups.It may well be concluded that direct electrical current potential 5.77 mA/cm2 was most effective than 11.82 mA/cm2.