Synthesis of some Phthalazine from Hydrazone of Amino Acids


A number of hydrazone (2a-h) were synthesiszed from the reaction of protected amino acid hydrazide and substituted benzaldehyde. The obtained products then treated with amyl alcohol saturated with HCl gas to give a number of substituted phthalazine (3a-h). The structures of the synthesized compounds were confirmed by IR spectra methods.