IMPLANT OF OXALOBACTER FORMIGENES INTO THE INTESTINAL TRACT OF LABORATORY RATS

Abstract

Two isolates of Oxalobacter formigenes were examined for their ability to colonize the intestinal tract of adult laboratory rats. These rats did not harbour O. formigenes. Both strains succeeded in colonizing the intestinal tract of adult rats fed a diet that contained 4 % sodium oxalate. Three days after rats were inoculated orally with 109 viable cells of the two strains, oxalate concentration in rat's urine markedly decreased. Both isolates were not detected in the faeces of inoculated rats fed diets that contained less than 3 % sodium oxalate