Abstract

Background:Different thyroid disorders may cause variation in serum protein fractions together with other biochemical parameters. Electrophoresis is one of the main important tools used to determine serum protein fractions.Aim of the study: To assess the possible utility of biochemical parameters and serum protein fractions in differentiating, classifying and may be aiding the diagnosis of different thyroid disorders.Patients and methods: A total of 145 subjects were enrolled in this study , they were 30 healthy individuals ( control group )and 115 patients with different thyroid disorders (patients group). The latter was subdivided into four other subject groups categorized according to the type of disorder. Parameters studied in this work included: Serum Total protein (Tp) and protein electrophoresis fractions (Albumin Alb ,α1 , α2 , β and γ globulin fractions).Results: There was a significant decrease in serum albumin level in all patient groups studied. On the other hand glycoprotein electrophorogrems reveled a variation in protein fraction that deepen on the type of thyroid disorders studied . Conclusion: This simple available technique might aid so much in detecting the activity of thyroid and the extent of its disorders, as well as

The article was added to IASJ on 2012-05-30

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