EFFECT OF SALINITY ON ANTIBIOTIC RESISTANCE IN STAPHYLOCOCCUS AUREUS

Abstract

Susceptibility of Staphylococcus aureus to gentamicin, nalidixic acid, ampicillin, amoxicillin and seven antiseptic agents: detol, ethanol (70 %), sodium hypochlorite, povidin iodine, iodine, hapitin, and septol, was evaluated using disc diffusion method on elevated NaCl containing media. Resistance to Ampicillin and Amoxicillin was changed to susceptibility when Staphylococcus aureus was cultured on this media. The diameter of the zone of inhibition has a direct relationship with the NaCl concentration in the media. Laboratory rats were infected experimentally by Staphylococcus aureus. Results prove that all those animals were unsuccessfully treated, since it is possible to isolate Staphylococcus aureus from their urine samples, by ampicillin or amoxicillin alone but they get cured when they received antibiotics in combination with NaCl injection