Histopathological Study of Placenta in Cases of Hypertension During Pregnancy

Abstract

This study was carried out in order to investigate the histopathological changes in the placenta of hypertensive pregnant women. A collection of forty placenta samples from hypertensive pregnant women associated with forty placenta samples from normal pregnancy selected as control group. The pregnant women were admitted to Al-Khansaa Maternity hospital in Mosul. The histopathological changes in hypertensive placenta included fibrosis with stenos is of maternal arteries, shedding and discontinuation of syncytial border in the decidua, hemorrhage inflammatory exudates and necrosis in the decidua basalis. Accumulation of huge amount of fibrinoid deposits was present in maternal decidua and large amount of collagen fibers surrounded the villous stroma and maternal decidua. A possible explanation for the results of this study is that the hypertension in pregnancy have enormous affect on inducing histopathological changes in the placenta of hypertensive pregnant women