Efficacy of Using Synchronized Nasal Intermittent Positive Pressure (SNIPPV) Versus Ordinary Continuous Positive Airway Pressure (CPAP) in Sick Neonate

Abstract

Background: Nasal continuous positive airway pressure (NCPAP) for respiratory support reduces the need of endotracheal intubation and mechanical ventilation. A new mode with continuous positive pressure including a CPAP with intermittent mechanical rate synchronized with breathing SNIPPV. Objectives: Assessing effectiveness and safety of this mode SNIPPV with the ordinary CPAP.Methods: A prospective study on neonates with apneas and/or respiratory distress or fit for extubation randomized to receive the ordinary CPAP group1or receive the SNIPPVgroup2.Result:18 case in each group, in both males needed more support than females, no death among group 1 while1 case died in the second group, Apgar score mean nearly same for both groups it was 7.2&9.2 at 1&5 minutes group1 compared to 6.9& 8.8 at 1&5minutes group 2,1case in each group got PIE,2 cases in group1 had PDA compared to 3cases in the group 2, no cases of group1cases failed while 4cases in group 2 failed this support(p 0.032), no cases in group one develop CLD compared to two cases group two, no intestinal perforation in both groups.Conclusion: According to the data there was no significant difference in short and long term outcome between the ordinary CPAP and the SNIPPV when they used for sick neonates.