Study of relationship between blood parameters and oxidant-antioxidant status of patients with unstable angina pectoris and myocardial infractions

Abstract

SUMMARYThe present study investigated the relationship between blood parameters and oxidant-antioxidant parameters of patients with unstable angina pectoris and myocardial infraction in Thi-Qar province / south of Iraq.. The results showed a significant elevation for each one of WBCs count, absolute neutrophil value and ESR in patients with unstable angina(UA) and myocardial infraction(AMI) when compared with control. Also a significant decrease was observed for each one of RBCs count, PCV, and Hb in both patient groups compared with control. The results of biochemical parameters explained a significant increase of malondialdehyde(MDA) and ceruloplasmin(Cp) in patients with UM and AMI compared with control group. Creatin phosphokinase(CPK) and lactate dehydrogenase(LDH) had a significant rising in patients with AMI , while there was a slight and non significant rising for both enzymes in patients with UM compared with control group. Albumin was decreased significantly in blood serum of AMI patients , while albumin level was not effected in blood serum of UA patients compared with control. Also, the results indicated the positive relationship between MDA and ESR,WBCs,absolute neutrophil value and ceruloplasmin in UA patient group , while in AMI patient group , the MDA was positively correlated with ESR,WBCs,absolute neutrophil value,ceruloplasmin ,CPK and LDH.In addition, the was a negative relationship between MDA and albumin in AMI patients.