Antibacterial Susceptibility Of Commonly Encountered Uropathogens In Al-Hussain Teaching Hospital-Thi-Qar Province: A Retrospective Study

Abstract

ABSTRACT: Background: Antibacterial resistance is an evolving problem which reflects the antibacterial prescription in our community. Such problem has great impact on proper management and consequences of urinary tract infection (UTI)Aim: To determine the relative role of uropathogens and their antibiotic susceptibility pattern in community-acquired urinary tract infection (UTI) in Al-Hussain Teaching Hospital/ Thi-Qar Province.Methodology: A retrospective study was carried out to review urine culture and antibiotic sensitivity testing from symptomatic outpatients visiting Al-Hussain Teaching Hospitals/ Thi-Qar Province over the period from June 2007 to June 2008. Results: Of 236 samples, 124(52.5%) were culture positive. Staphylococci and Escherichia coli were the leading cause of UTI accounting for 75% of all isolates. The rates and roles of other pathogens, including Klebsiella species (11%), Pseudomonas species (8%), Enterobacter, Proteus, and Streptococci were responsible for the remaining 6%. More than 75% of isolated Staphylococci and Escherichia coli were sensitive to nitrofurantoin and amikacin, while more than 60% were sensitive to ciprofloxacin. Sensitivity to commonly prescribed antibacterials as co-trimoxazole, amoxicillin,ampicillin and gentamicin were less. Conclusion: Common uropathogens were highly sensitive to nitrofurantoin, amikacin and to lesser extent to ciprofloxacin, while exhibiting low sensitivity pattern against commonly prescribed antibiotics including co-trimoxazole, amoxicillin, ampicillin, nalidixic acid and gentamicin.