فعالية إنزيم الزانثين اوكسيديز Xanthine oxidaseوعلاقته بمستوى فيتامين (C, E)

Abstract

AbstractThe specific activity of Xanthine oxidase in serum of atherosclerotic patients was determined and correlated with (MDA), Iron element and levels vitamins (C, E). The patients were divided into two groups according to the period of disease as follows.1st group consists of 50 patients, period of disease (2-4) years. 2nd group consists of 50 patients, period of disease < 4 years. The control was consisted of 50 healthy persons.Theresults revealed an increase in the specific activity of Xanthine oxidase with duration of disease especially in the 2nd group compared to control group. Moreover, an increase in (MDA) and (Fe) levels and low levels in vitamins (C, E) in sera of patients with duration of disease were detected. This could be an indication of the damage in the arterial wall due to lipid peroxidation and generation of free radicals.

Keywords

Chemistry